General Cell Based Assays
ABclonal Technology 12 Lipoxygenase/ALOX12
This gene encodes a member of the lipoxygenase family of proteins The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins The encoded enzyme and its reaction products have been shown to regulate platelet function Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients Allelic variants in this gene may be associated with susceptibility to toxoplasmosis Multiple pseudogenes of this gene have been identified in the human genome
Meso Scale Discovery RPLEX HUM Nucleotidase ASY
The R-Plex Human 5 -Nucleotidase Assay from Meso Scale Diagnostics measures 5 -Nucleotidase in human serum plasma and cell culture supernatants using electrochemiluminescence (ECL) technology It offers high sensitivity a wide dynamic range and low sample volume requirements This assay quantifies 5 -Nucleotidase a glycoprotein in purine metabolism aiding in studying liver disease cancers and gout With a testing time of 3 5 hours it enables efficient analysis of 5 -Nucleotidase levels
ABclonal Technology Lamin A/C Rabbit pAb
The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Cayman Chemical 33-BCRP InhIbItr 1mg
A BCRP inhibitor; sensitizes mitoxantrone-resistant H460/MX20 cells to mitoxantrone-induced cell death alone and in combination with UV radiation; sensitizes KB-C2 cells overexpressing P-gp to colchicine-induced cell death; increases intracellular accumulation of mitoxantrone in H460/MX20 cells at 5 µM
Eurofins Discoverx PathHunter Human CCL25 (CCR9) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CCL25 (CCR9) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCR9 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF CD16a (FcgRIIIa, V158) Cellular Binding Kit, 500 Assay Points
HTRF CD16a (FcgRIIIa, V158) Cellular Binding Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF acetyl K40 α-Tubulin Detection Kit, 500 Assay Points
HTRF acetyl K40 α-Tubulin Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-AKT3 (Ser473) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-AKT3 (Ser473) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Total VASP Detection Kit, 500 Assay Points
HTRF Human & Mouse Total VASP Detection Kit, 500 Assay Points
Abcam Alkaline Phosphatase Assay Kit (Colorimetric)
Alkaline Phosphatase Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx AssayComplete Cell Plating 16 Reagent, 500. (93-0563R16B)
AssayComplete Cell Plating 16 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx AssayComplete Cell Culture Kit-101, (92-3101G)
AssayComplete Cell Culture Kit-101 is an optimized media kit intended for use in culturing and propagating Eurofins DiscoverX cell lines. This kit contains the base medium, relevant serum, and pen/strep required to produce a full cell culture medium for optimal cell culture results. This product is provided as a 3-component kit which will produce approximately 550 mL of finished media. Please refer to cell line specific datasheet to determine the recommended cell culture kit. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Cayman Chemical NFAT InhIbItr 5mg
A peptide inhibitor of NFAT; binds to the NFAT recognition site on calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity at 100 µM; inhibits the dephosphorylation of NFAT in HEK293T lysates expressing NFAT1, -2, or -4; inhibits NFAT activation in RAW 264.7 macrophages, EA.hy926 endothelial cells, and isolated mouse thoracic aorta VSMCs (IC50s = 29.1, 30.2, and 45.7 µM, respectively, in reporter assays)
Cayman Chemical DIhydroethIdIum 10mg
A fluorescent dye to monitor superoxide production; ex/em = 490/590 nm; has been used to detect ROS and intracellular superoxide in vitro